Which one of the following organisms causes Tyzzer disease?
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Clostridium piliforme infection (old name, Bacillus piliformis) is the causative agent of Tyzzer disease. Think hepatitis and acute death in icteric foals 7-40 days old. Dogs, cats, and calves can also be affected.
On necropsy see HUGE LIVER with disseminated, multifocal areas of necrosis, thick, congested intestines, focal myocarditis.