Question of the Day

This is a classic presentation for dilated cardiomyopathy (DCM); perform thoracic radiographs to evaluate for congestive heart failure. Perform electrocardiogram to better assess the cardiac rythm. Use echocardiography to confirm the diagnosis. 

Consider veterinary point of care ultrasound (POCUS) to assess for pleural effusion and alveolar infiltrates.

Tx to control arrhythmia and diminish clinical signs. Therapy may include diuretics (e.g., furosemide), positive inotropes (e.g., pimobendan), angiotensin converting enzyme inhibitors (e.g., enalapril) and antiarrhythmics (e.g., diltiazem, sotalol).

Px is guarded, especially for Dobermans – with Tx may live six months to two years. Large and giant breeds are at increased risk, including Irish wolfhounds and great Danes. Boxers can develop arrhythmogenic right ventricular cardiomyopathy, distinct from DCM.

Dobermans have two genetic mutations that can lead to development of DCM: PDK4 and DCM2. Each mutation independently can lead to DCM: dogs affected with both are 30 times more likely to develop DCM than a normal dog.