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The islets of Langerhans are found in the pancreas and contain endocrine cells that secrete insulin and other hormones.
Remember, the pancreas also has a digestive function. This is the exocrine pancreas and is made up of acinar cells that produce digestive enzymes.
In animals, the most important islets cells are: – Alpha cells produce glucagon – Beta cells produce insulin (60-70% of total islet cells) – Delta cells produce somatostatin
Type 1 (insulin-dependent) diabetes mellitus is a classic example of pancreatic endocrine disease due to a deficiency of pancreatic beta cells (typically due to immune-mediated destruction of the beta cells).
